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Characterizing mitochondrial features in osteoarthritis through integrative multi-omics and machine learning analysis

4 Jul 2024

Abstract excerpt

Purpose: Osteoarthritis (OA) stands as the most prevalent joint disorder. Mitochondrial dysfunction has been linked to the pathogenesis of OA. The main goal of this study is to uncover the pivotal role of mitochondria in the mechanisms driving OA development. Materials and methods: We acquired seven bulk RNA-seq datasets from the Gene Expression Omnibus (GEO) database and examined the expression levels of...

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PMID: 39026663
DOI: 10.3389/fimmu.2024.1414301

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