Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The associations between dysregulation of human blood metabolites and lung cancer risk: evidence from genetic data.

BMC cancer - 18 Jul 2024

Wu Gujie, Liu Jun, Shi Haochun, Pan Binyang, Li Min, Wang Xiaolin, Li Yao, Cheng Lin, Guo Weigang, Huang Yiwei

Abstract excerpt

BACKGROUND: Metabolic dysregulation is recognized as a significant hallmark of cancer progression. Although numerous studies have linked specific metabolic pathways to cancer incidence, the causal relationship between blood metabolites and lung cancer risk remains unclear. METHODS: Genomic data from 29,266 lung cancer patients and 56,450 control individuals from the Transdisciplinary Research in Cancer of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Lung Neoplasms

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 39026146
DOI: 10.1186/s12885-024-12416-1
PMCID: PMC11256634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The associations between dysregulation of human blood metabolites and lung cancer risk: evidence from genetic data.PMID 39026146Read ↗

Exploring Metabolites as Therapeutic Targets in Lung Cancer: Insights from Mendelian RandomizationSemantic proximity Read ↗

Causal Effects of Genetically Determined Lipidome on Lung Cancer and Its Subtypes: A Mendelian Randomization StudySemantic proximity Read ↗

Lipid metabolism gene-wide profile and survival signature of lung adenocarcinomaSemantic proximity Read ↗

Lipid metabolism gene-wide profile and survival signature of lung adenocarcinomaSemantic proximity Read ↗

Serum Lipid Levels, Genetic Risk, and Lung Cancer Incidence: A Large Prospective Cohort Study.Semantic proximity Read ↗

A risk score model based on lipid metabolism-related genes could predict response to immunotherapy and prognosis of lung adenocarcinoma: a multi-dataset study and cytological validationSemantic proximity Read ↗

Chronic Obstructive Pulmonary Disease Influence on Lung Cancer Risk Through Blood Metabolite Mediation: A Two-Sample Mendelian Randomisation and Mediation Analysis.Semantic proximity Read ↗

Histological and genetic features and therapeutic responses of lung cancers explored via the global analysis of their metabolome profile.Semantic proximity Read ↗

Circulating Isovalerylcarnitine and Lung Cancer Risk: Evidence from Mendelian Randomization and Prediagnostic Blood Measurements.Semantic proximity Read ↗

Inflammatory factors and risk of lung adenocarcinoma: a Mendelian randomization study mediated by blood metabolites.Semantic proximity Read ↗

Plasma proteometabolome in lung cancer: exploring biomarkers through bidirectional Mendelian randomization and colocalization analysisSemantic proximity Read ↗

Novel Lipid Metabolism-Related Gene Signature in Lung Adenocarcinoma Patients Experiencing Lymph Node MetastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.