Article
Histological and genetic features and therapeutic responses of lung cancers explored via the global analysis of their metabolome profile.
Lung cancer (Amsterdam, Netherlands) - 1 Feb 2025
Narita Daisuke, Hishinuma Eiji, Ebina-Shibuya Risa, Miyauchi Eisaku, Matsukawa Naomi, Motoike Ikuko N, Kinoshita Kengo, Koshiba Seizo, Tsukita Yoko, Notsuda Hirotsugu, Kimura Nozomu, Saito Ryota, Murakami Koji, Fujino Naoya, Ichikawa Tomohiro, Yamada Mitsuhiro, Tamada Tsutomu, Sugiura Hisatoshi
Abstract excerpt
BACKGROUND: Lung cancer is the deadliest disease globally, with more than 120,000 diagnosed cases and more than 75,000 deaths annually in Japan. Several treatment options for advanced lung cancer are available, and the discovery of biomarkers will be useful for personalized medicine. Using metabolome analysis, we aimed to identify biomarkers for diagnosis and treatment response by examining the changes in...
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