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Article

Fitness landscapes of human microsatellites.

PLoS genetics - 1 Dec 2024

Haasl Ryan J, Payseur Bret A

Abstract excerpt

Advances in DNA sequencing technology and computation now enable genome-wide scans for natural selection to be conducted on unprecedented scales. By examining patterns of sequence variation among individuals, biologists are identifying genes and variants that affect fitness. Despite this progress, most population genetic methods for characterizing selection assume that variants mutate in a simple manner and at a...

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Identifiers

PMID: 39775235
DOI: 10.1371/journal.pgen.1011524
PMCID: PMC11734926

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