Article
Independent inheritance of cognition and bipolar disorder in a family sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2025
D'Amico Alexander, Sung Heejong, Arbona-Lampaya Alejandro, Freifeld Ally, Hosey Katie, Garcia Joshua, Lacbawan Ley, Besançon Emily, Kassem Layla, Akula Nirmala, Knowles Emma E M, Dickinson Dwight, McMahon Francis J
Abstract excerpt
Cognitive deficits in people with bipolar disorder (BD) may be the result of the illness or its treatment, but they could also reflect genetic risk factors shared between BD and cognition. We investigated this question using empirical genetic relationships within a sample of patients with BD and their unaffected relatives. Participants with bipolar I, II, or schizoaffective disorder ("narrow" BD, n = 69), related...
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