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Article

Bidirectional genetic overlap between bipolar disorder and intelligence.

BMC medicine - 30 Nov 2022

Shang Meng-Yuan, Wu Yong, Zhang Chu-Yi, Qi Hao-Xiang, Zhang Qing, Huo Jin-Hua, Wang Lu, Wang Chuang, Li Ming

Abstract excerpt

BACKGROUND: Bipolar disorder (BD) is a highly heritable psychiatric illness exhibiting substantial correlation with intelligence. METHODS: To investigate the shared genetic signatures between BD and intelligence, we utilized the summary statistics from genome-wide association studies (GWAS) to conduct the bivariate causal mixture model (MiXeR) and conjunctional false discovery rate (conjFDR) analyses. Subsequent...

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Identifiers

PMID: 36447210
DOI: 10.1186/s12916-022-02668-8
PMCID: PMC9710050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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