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Data-driven cognitive phenotypes in subjects with bipolar disorder and their clinical markers of severity.

Psychological medicine - 1 Jul 2022

Rabelo-da-Ponte Francisco Diego, Lima Flavia Moreira, Martinez-Aran Anabel, Kapczinski Flávio, Vieta Eduard, Rosa Adriane Ribeiro, Kunz Maurício, Czepielewski Leticia Sanguinetti

Abstract excerpt

BACKGROUND: Subjects with bipolar disorder (BD) show heterogeneous cognitive profile and that not necessarily the disease will lead to unfavorable clinical outcomes. We aimed to identify clinical markers of severity among cognitive clusters in individuals with BD through data-driven methods. METHODS: We recruited 167 outpatients with BD and 100 unaffected volunteers from Brazil and Spain that underwent a...

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PMID: 33050962
DOI: 10.1017/S0033291720003499

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