Article
Insertion with long target duplication in polymyxin B-induced resistant mutant of Salmonella.
Journal of global antimicrobial resistance - 1 Sept 2024
Zhang Tongtong, Jiang Huifen, Zhao Ying, Yao Tingting, Li Rui
Abstract excerpt
OBJECTIVES: A Salmonella enterica subsp. diarizonae (hereafter S. diarizonae) clinical strain S499 demonstrated unique genomic features. The strain S499 was treated with polymyxin B in vitro to investigate the mechanism of resistance. METHODS: S499 was treated with polymyxin B by increasing concentration gradually to obtain a resistant mutant S499V. Whole genomes of the two strains were sequenced using Illumina...
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