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Novel trimethoprim resistance gene dfrA34 identified in Salmonella Heidelberg in the USA

22 Aug 2018

Abstract excerpt

Background: Trimethoprim/sulfamethoxazole is a synthetic antibiotic combination recommended for the treatment of complicated non-typhoidal Salmonella infections in humans. Resistance to trimethoprim/sulfamethoxazole is mediated by the acquisition of mobile genes, requiring both a dfr gene (trimethoprim resistance) and a sul gene (sulfamethoxazole resistance) for a clinical resistance phenotype (MIC ≥4/76 mg/L)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30202900
DOI: 10.1093/jac/dky373

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