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Article

Influence of CYP2C19 loss-of-function variants on the metabolism of clopidogrel in patients from north-western China.

Journal of clinical pharmacy and therapeutics - 1 Jun 2015

Lin R, Zhang L, Zhang P, Zhou L, Liu T, Li Y, Zhang W, Wang W, Zhang J

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: Variation of the cytochrome P450 2C19 gene coding for the CYP2C19 enzyme has been reported to be associated with clopidogrel response variability. The activity of the CYP2C19 enzyme is genetically influenced by polymorphisms of its gene. METHODS: This study was conducted to assess the impact of CYP2C19 polymorphism on the clopidogrel metabolism, indirectly selecting the plasma...

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Source

Identifiers

PMID: 25810245
DOI: 10.1111/jcpt.12254

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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