BCR::ZNF711 and BCR::CYLC2 Fusions: Novel BCR Fusions Expanding the Molecular Spectrum of Gene Fusions in Melanoma

Abstract excerpt

To the Editor: Since the discovery of the breakpoint cluster region (BCR)::Abelson murine leukemia viral oncogene 1 (ABL) fusion in chronic myeloid leukemia, BCR has been found to engage in fusion events with various tyrosine kinases, including fibroblast growth factor receptor 1, platelet-derived growth factor receptor alpha, ret proto-oncogene, and Janus kinase 2, across a spectrum of hematological...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CAR-T cell therapy research
• Share to Protein Degradation and Inhibitors
• Share to Virus-based gene therapy research