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Article

Histopathologic and molecular characterization of BAP-1-inactivated melanoma.

Journal of cutaneous pathology - 1 Apr 2023

Miller Elisabeth M, Linos Konstantinos, Bacchi Carlos E, Gru Alejandro A, Raghavan Shyam S

Abstract excerpt

BACKGROUND: BRCA1-associated protein 1 (BAP-1) is a deubiquitylase that functions as a tumor suppressor, regulating multiple cellular processes including cell cycle control, differentiation, cell death, and DNA repair. BAP-1-inactivated melanocytic tumors (BIMTs) have recently been described and are characterized by epithelioid cytomorphology, are often clonal in appearance, and typically do not recur or show...

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Identifiers

PMID: 36285428
DOI: 10.1111/cup.14346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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