SBF1::BRAF-Fused Melanoma With Prominent Rhabdoid Morphology and Reed–Sternberg-Like Cells: Potential Morphologic Clues to BRAF-Fused Melanomas of Non-Spitz Lineage?

Abstract excerpt

To the Editor: Spitz melanomas exhibit the cytomorphologic characteristics of Spitz nevi, while also displaying hallmark features of malignancy. In contrast, non-Spitz melanomas—including superficial spreading, nodular, lentigo maligna, and acral subtypes—lack cytomorphologic evidence of Spitz lineage and represent conventional forms of melanoma. Unlike Spitz melanocytic neoplasms, which frequently harbor...

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