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Article

Building on the clinical applicability of ctDNA analysis in non-metastatic pancreatic ductal adenocarcinoma.

Scientific reports - 13 Jul 2024

Labiano Ibone, Huerta Ana E, Alsina Maria, Arasanz Hugo, Castro Natalia, Mendaza Saioa, Lecumberri Arturo, Gonzalez-Borja Iranzu, Guerrero-Setas David, Patiño-Garcia Ana, Alkorta-Aranburu Gorka, Hernández-Garcia Irene, Arrazubi Virginia, Mata Elena, Gomez David, Viudez Antonio, Vera Ruth

Abstract excerpt

Pancreatic ductal adenocarcinoma represents one of the solid tumors showing the worst prognosis worldwide, with a high recurrence rate after adjuvant or neoadjuvant therapy. Circulating tumor DNA analysis raised as a promising non-invasive tool to characterize tumor genomics and to assess treatment response. In this study, surgical tumor tissue and sequential blood samples were analyzed by next-generation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39003322
DOI: 10.1038/s41598-024-67235-y
PMCID: PMC11246447

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