Article
From modules to medicine: How modular domains and their associated networks can enable personalized medicine.
FEBS letters - 14 Aug 2012
Haura Eric B
Abstract excerpt
Unveiling of cancer genomes is unleashing new therapeutic strategies for cancer. With cancer parts lists in hand, new approaches to personalized medicine can be developed by understanding the assembly of cancer machines using modular domains in proteins and their associated networks. Using the Src-homology-2 (SH2) domain as an example, new profiling approaches can discern global patterns of tyrosine...
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