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Article

Genome-wide polygenic risk score for rheumatoid arthritis prediction in postmenopausal women.

The journal of gene medicine - 1 Jan 2024

Xu Yingke, Wu Qing

Abstract excerpt

BACKGROUND: Rheumatoid arthritis (RA), a common autoimmune disease, exhibits a vital genetic component. Polygenic risk scores (PRS) derived from genome-wide association studies (GWAS) offer potential utility in predicting disease susceptibility. The present study aimed to develop and validate a PRS for predicting RA risk in postmenopausal women. METHODS: The study developed a novel PRS using 225,000 genetic...

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Identifiers

PMID: 38282146
DOI: 10.1002/jgm.3659
PMCID: PMC10823178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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