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Article

Mutations in the pmrB gene constitute the major mechanism underlying chromosomally encoded colistin resistance in clinical Escherichia coli.

Journal of global antimicrobial resistance - 1 Sept 2024

Lin Jung-Chung, Kristopher Siu Leung-Kei, Chang Feng-Yee, Wang Ching-Hsun

Abstract excerpt

OBJECTIVES: The mechanisms underlying chromosomally encoded colistin resistance in Escherichia coli remain insufficiently investigated. In this study, we investigated the contribution of various pmrB mutations from E. coli clinical isolates to colistin resistance. METHODS: The resistance mechanisms in eight mcr-negative colistin-resistant E. coli isolates obtained from a nationwide surveillance program in Taiwan...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38996871
DOI: 10.1016/j.jgar.2024.06.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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