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Article

The Role of Endometriosis in Intestinal Inflammation: A Combined Mendelian Randomization and Cellular Study.

Journal of cellular and molecular medicine - 1 Sept 2025

Li Zhigang, Wang Fang, Kang Ernv, Zhen Xiaoguang, Liu Jianli, Wang Wenhao

Abstract excerpt

This study aims to assess whether endometriosis causally increases the risk of IBD through Mendelian randomisation (MR) analysis and to elucidate potential mechanisms using in vitro experiments. A two-sample Mendelian randomisation (MR) analysis was conducted using genome-wide association study datasets for endometriosis and IBD, including ulcerative colitis and Crohn's disease. Causal inference was assessed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40922382
DOI: 10.1111/jcmm.70799
PMCID: PMC12417327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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