Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitophagy and clear cell renal cell carcinoma: insights from single-cell and spatial transcriptomics analysis

27 Jun 2024

Abstract excerpt

Background Clear Cell Renal Cell Carcinoma (ccRCC) is the most common type of kidney cancer, characterized by high heterogeneity and complexity. Recent studies have identified mitochondrial defects and autophagy as key players in the development of ccRCC. This study aims to delve into the changes in mitophagic activity within ccRCC and its impact on the tumor microenvironment, revealing its role in tumor cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Ferroptosis and cancer prognosis
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38994370
DOI: 10.3389/fimmu.2024.1400431

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitophagy and clear cell renal cell carcinoma: insights from single-cell and spatial transcriptomics analysisPMID 38994370Read ↗

Integrated the analysis of single-cell and bulk RNA-sequencing to predict renal cell carcinoma by identifying signature based on Mitophagy-related GenesSemantic proximity Read ↗

Single-Cell RNA Sequencing in Multiple Pathologic Types of Renal Cell Carcinoma Revealed Novel Potential Tumor-Specific MarkersSemantic proximity Read ↗

Integrated molecular analysis of clear-cell renal cell carcinoma.Semantic proximity Read ↗

Multi-omic profiling of clear cell renal cell carcinoma identifies metabolic reprogramming associated with disease progressionSemantic proximity Read ↗

Unveiling Biomarkers: A Study on Mitocytosis-Related Genes Across Multiple CancersSemantic proximity Read ↗

Multi-omics analysis reveals the role of ribosome biogenesis in malignant clear cell renal cell carcinoma and the development of a machine learning-based prognostic modelSemantic proximity Read ↗

The Deubiquitinase USP2 Inhibits Clear Cell Renal Cell Carcinoma by Activating the p53 Signaling Pathway and Inducing FerroptosisSemantic proximity Read ↗

Deep visual multi-omics profiling reveals mechanisms that underlie cancer cell differentiation and aggressiveness in clear cell renal cell carcinomaSemantic proximity Read ↗

Deciphering the molecular landscape: integrating single-cell transcriptomics to unravel myofibroblast dynamics and therapeutic targets in clear cell renal cell carcinomasSemantic proximity Read ↗

Dissecting order amidst chaos of programmed cell deaths: construction of a diagnostic model for KIRC using transcriptomic information in blood-derived exosomes and single-cell multi-omics data in tumor microenvironmentSemantic proximity Read ↗

Mechanisms and Functions of Mitophagy and Potential Roles in Renal DiseaseSemantic proximity Read ↗

Deciphering Tumor Metastasis and Immune Inhibitory Signature of Clear Cell Renal Cell Carcinoma by Single-Cell Transcriptome AnalysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.