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Differences in the Prognostic Role of Age, Extent of Resection, and Tumor Grade between Astrocytoma IDHmt and Oligodendroglioma: A Single-Center Cohort Study.

Clinical cancer research : an official journal of the American Association for Cancer Research - 3 Sept 2024

van der Vaart Thijs, Wijnenga Maarten M J, van Garderen Karin, Dubbink Hendrikus J, French Pim J, Smits Marion, Dirven Clemens M F, Kros Johan M, Vincent Arnaud J P E, van den Bent Martin J

Abstract excerpt

PURPOSE: IDH-mutant glioma is classified as oligodendroglioma or astrocytoma based on 1p19q-codeletion. Whether prognostic factors are similar between these tumor types is not well understood. EXPERIMENTAL DESIGN: Retrospective cohort study. Molecular characterization was performed with targeted next-generation sequencing. Tumor volumes were calculated using semiautomatic 3D segmentation on all pre- and...

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PMID: 38990096
DOI: 10.1158/1078-0432.CCR-24-0901

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