Prognostic stratification of newly diagnosed IDH-mutant gliomas by [18F]fluoroethyltyrosine and [11C]methionine PET: A retrospective, bicentric cohort study.

doi:10.1093/neuonc/noaf196

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Article

Prognostic stratification of newly diagnosed IDH-mutant gliomas by [18F]fluoroethyltyrosine and [11C]methionine PET: A retrospective, bicentric cohort study.

Neuro-oncology - 1 Dec 2025

Mair Maximilian J, Werner Jan-Michael, Weller Jonathan, Barci Enio, Katzendobler Sophie, Isakaj Jera, Berchtold Luzia, Aras Thedora, Stürzl Roman, Hennenberg Juliane, Reis Jonas, Puhr Hannah C, Schabhüttl Thomas, Kiesel Barbara, Widhalm Georg, Wöhrer Adelheid, Nakuz Thomas, Hacker Marcus, Furtner Julia, Schönecker Stephan, Harter Patrick N, von Baumgarten Louisa, Berghoff Anna S, Thon Niklas, Preusser Matthias, Albert Nathalie L

Abstract excerpt

BACKGROUND: Improved prognostic stratification, including imaging-based parameters, is needed to guide treatment decisions in IDH-mutant glioma. METHODS: In this bicentric retrospective study, 457 patients with IDH-mutant glioma and [18F]fluoroethyltyrosine or [11C]methionine positron emission tomography (PET) prior to radiotherapy or systemic treatment were included. Associations of maximum and mean...

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PMID: 40856188
DOI: 10.1093/neuonc/noaf196
PMCID: PMC12916739

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