Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An enterococcal phage-derived enzyme suppresses graft-versus-host disease

10 Jul 2024

Abstract excerpt

Abstract Changes in the gut microbiome have pivotal roles in the pathogenesis of acute graft-versus-host disease (aGVHD) after allogenic haematopoietic cell transplantation (allo-HCT)1–6. However, effective methods for safely resolving gut dysbiosis have not yet been established. An expansion of the pathogen Enterococcus faecalis in the intestine, associated with dysbiosis, has been shown to be a risk factor for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Cystic Fibrosis Research Advances
Share to Hematopoietic Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38987594
DOI: 10.1038/s41586-024-07667-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An enterococcal phage-derived enzyme suppresses graft-versus-host diseasePMID 38987594Read ↗

Engrafting gut bacteriophages have potential to modulate microbial metabolism in fecal microbiota transplantationSemantic proximity Read ↗

Engrafting gut bacteriophages have potential to modulate microbial metabolism in fecal microbiota transplantationSemantic proximity Read ↗

Bacteriophage resistance alters antibiotic mediated intestinal expansion of enterococciSemantic proximity Read ↗

Bacteriophage endolysins as a potential weapon to combat Clostridioides difficile infectionSemantic proximity Read ↗

Exploring the therapeutic potential of endolysin CD27L_EAD against Clostridioides difficile infectionSemantic proximity Read ↗

Bacteriophage Rescue Therapy of a Vancomycin-Resistant Enterococcus faecium Infection in a One-Year-Old Child following a Third Liver TransplantationSemantic proximity Read ↗

Faecal microbiota transplantations and the role of bacteriophagesSemantic proximity Read ↗

Myoviridae phage PDX kills enteroaggregative Escherichia coli without human microbiome dysbiosisSemantic proximity Read ↗

The Enterococcus faecalis cytolysin: a novel toxin active against eukaryotic and prokaryotic cellsSemantic proximity Read ↗

Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatmentsSemantic proximity Read ↗

Enterococcus faecium Biofilm Formation: Identification of Major Autolysin AtlA <sub>Efm</sub> , Associated Acm Surface Localization, and AtlA <sub>Efm</sub> -Independent Extracellular DNA ReleaseSemantic proximity Read ↗

Insertion sequence-mediated phage resistance contributes to attenuated colonization of cytolytic Enterococcus faecalis variants in the gutSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.