Enterococcus faecium Biofilm Formation: Identification of Major Autolysin AtlA _Efm , Associated Acm Surface Localization, and AtlA _Efm -Independent Extracellular DNA Release

Abstract excerpt

Enterococcus faecium is an important multidrug-resistant nosocomial pathogen causing biofilm-mediated infections in patients with medical devices. Insight into E. faecium biofilm pathogenesis is pivotal for the development of new strategies to prevent and treat these infections. In several bacteria, a major autolysin is essential for extracellular DNA (eDNA) release in the biofilm matrix, contributing to biofilm...

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