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Engrafting gut bacteriophages have potential to modulate microbial metabolism in fecal microbiota transplantation

20 Jun 2025

Abstract excerpt

BACKGROUND: Fecal microbiota transplantation (FMT) is widely used to treat severe infections and investigated for the treatment of complex diseases. The therapeutic efficacy of FMT is related to the successful engraftment of bacteriophages from healthy donors to recipients. However, gut bacteriophage contributions to FMT engraftment and treatment outcomes remain unclear. METHODS: The gut phageome from previously...

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PMID: 40542451
DOI: 10.1186/s40168-025-02046-5

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