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Article

A genome-wide association study implicates the olfactory system in Drosophila melanogaster diapause-associated lifespan extension and fecundity.

eLife - 22 Jul 2025

Easwaran Sreesankar, Montell Denise J

Abstract excerpt

The effects of environmental stress on animal life are gaining importance with climate change. Diapause is a dormancy program that occurs in response to an adverse environment, followed by resumption of development and reproduction upon the return of favorable conditions. Diapause is a complex trait, so we leveraged the Drosophila Genetic Reference Panel (DGRP) lines and conducted a genome-wide association study...

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PMID: 40693912
DOI: 10.7554/eLife.98142
PMCID: PMC12283071

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