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Article

Sodium valproate effects on the morphological and neurobehavioral phenotype of zebrafish.

Environmental toxicology and pharmacology - 1 Sept 2024

Caioni Giulia, Merola Carmine, Perugini Monia, Angelozzi Giovanni, Amorena Michele, Benedetti Elisabetta, Lucon-Xiccato Tyrone, Bertolucci Cristiano

Abstract excerpt

The anticonvulsant sodium valproate (SV) is frequently administered as a medicament but bears several negative effects in case of exposure during development. We analyzed extensively these early development effects of using the zebrafish model. Zebrafish embryos were exposed as eggs to two sublethal concentrations of SV, 10 and 25 mg/L. A general embryo toxicity analysis revealed extended anomalies in the...

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Source

Identifiers

PMID: 38977114
DOI: 10.1016/j.etap.2024.104500

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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