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Article

Teratogenic Potential of Antiepileptic Drugs in the Zebrafish Model

1 Jan 2013

Abstract excerpt

The zebrafish model is an attractive candidate for screening of developmental toxicity during early drug development. Antiepileptic drugs (AEDs) arouse concern for the risk of teratogenicity, but the data are limited. In this study, we evaluated the teratogenic potential of seven AEDs (carbamazepine (CBZ), ethosuximide (ETX), valproic acid (VPN), lamotrigine (LMT), lacosamide (LCM), levetiracetam (LVT), and...

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Identifiers

PMID: 24324971
DOI: 10.1155/2013/726478

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