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Zebrafish embryonically exposed to valproic acid present impaired retinal development and sleep behavior

28 Aug 2023

Abstract excerpt

Prenatal exposure to valproic acid (VPA), a drug widely used to treat epilepsy and bipolar disorder, is an environmental risk factor for autism spectrum disorder (ASD). VPA has been used to reproduce the core symptoms of ASD in animal model organisms, including zebrafish. Visual system functioning is essential in the interpretation of social conditions and plays an important role of several behavioral responses....

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PMID: 37638671
DOI: 10.1002/aur.3010

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