Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The immunogenic potential of bacterial flagella for Salmonella-mediated tumor therapy.

International journal of cancer - 15 Jul 2020

Felgner Sebastian, Spöring Imke, Pawar Vinay, Kocijancic Dino, Preusse Matthias, Falk Christine, Rohde Manfred, Häussler Susanne, Weiss Siegfried, Erhardt Marc

Abstract excerpt

Genetically engineered Salmonella Typhimurium are potent vectors for prophylactic and therapeutic measures against pathogens as well as cancer. This is based on the potent adjuvanticity that supports strong immune responses. The physiology of Salmonella is well understood. It simplifies engineering of both enhanced immune-stimulatory properties as well as safety features, thus, resulting in an appropriate balance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Intravenous
Share to Colonic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flagella

Share to Microscopy, Electron, Scanning

Share to Proton-Translocating ATPases

Share to RAW 264.7 Cells

Share to Salmonella typhimurium

Share to Xenograft Model Antitumor Assays

Source

Identifiers

PMID: 31755108
DOI: 10.1002/ijc.32807

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The immunogenic potential of bacterial flagella for Salmonella-mediated tumor therapy.PMID 31755108Read ↗

Two-step enhanced cancer immunotherapy with engineered Salmonella typhimurium secreting heterologous flagellin.Semantic proximity Read ↗

A self-lysed attenuated Salmonella platform with flagellar displaying mediates tumor therapySemantic proximity Read ↗

Attenuated mutants of Salmonella enterica Typhimurium mediate melanoma regression via an immune response.Semantic proximity Read ↗

Amino acids 89-96 of Salmonella typhimurium flagellin represent the major domain responsible for TLR5-independent adjuvanticity in the humoral immune response.Semantic proximity Read ↗

Bacterial flagellar diversity and significance in pathogenesis.Semantic proximity Read ↗

Enhancement of host immune responses by oral vaccination to Salmonella enterica serovar Typhimurium harboring both FliC and FljB flagella.Semantic proximity Read ↗

Advances in the development ofSalmonella‐based vaccine strategies for protection against Salmonellosis in humansSemantic proximity Read ↗

The Role of Flagellin B in Vibrio anguillarum-Induced Intestinal Immunity and Functional Domain Identification.Semantic proximity Read ↗

Crystal structure of <i>E. coli</i> Nissle 1917 flagellin reveals novel features that modulate bacterial motility but not TLR5 recognitionSemantic proximity Read ↗

Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro.Semantic proximity Read ↗

Regulation of Flagellum Biosynthesis in Response to Cell Envelope Stress in Salmonella enterica Serovar TyphimuriumSemantic proximity Read ↗

Outer membrane vesicles derived from <i>Salmonella</i> Typhimurium can deliver <i>Shigella flexneri</i> 2a O-polysaccharide antigen to prevent lethal pulmonary infection in miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.