Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Is the Homologous Recombination Repair Mutation Defined by a 15-Gene Panel Associated with the Prognosis of Epithelial Ovarian Cancer?

Molecular diagnosis & therapy - 1 Sept 2024

Liu Yi, Chen Xiaojun, Lu Huaiwu, Wu Xin, Liu Xuehan, Xu Fei, Ye Dongdong, Ding Bo, Lu Xiaoyan, Qiu Ling, Zhu Jing, Wang Yingying, Huang Xinya, Shen Zhen, Zhu Tao, Shen Yang, Zhou Ying

Abstract excerpt

BACKGROUND: There is no consensus regarding the specific genes included in the homologous recombination repair (HRR) gene panel for identifying the HRR deficiency (HRD) status and predicting the prognosis of epithelial ovarian cancer (EOC) patients. OBJECTIVE: We aimed to explore a 15-gene panel involving the HRR pathway as a predictive prognostic indicator in Chinese patients newly diagnosed with EOC. PATIENTS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Carcinoma, Ovarian Epithelial

Share to Germ-Line Mutation

Share to Ovarian Neoplasms

Share to Poly(ADP-ribose) Polymerase Inhibitors

Share to Recombinational DNA Repair

Source

Identifiers

PMID: 38967864
DOI: 10.1007/s40291-024-00726-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is the Homologous Recombination Repair Mutation Defined by a 15-Gene Panel Associated with the Prognosis of Epithelial Ovarian Cancer?PMID 38967864Read ↗

Association of homologous recombination repair gene mutation with clinical prognosis in histological subtypes of epithelial ovarian cancer patients.Semantic proximity Read ↗

The clinical pathological characteristics and prognostic Relevance of Homologous Recombination Repair Gene Mutations in Ovarian Cancer Patients：A Retrospective Cohort StudySemantic proximity Read ↗

Germline and somatic mutations in homologous recombination genes among Chinese ovarian cancer patients detected using next-generation sequencing.Semantic proximity Read ↗

Whole exome sequencing-based homologous recombination deficiency test for epithelial ovarian cancerSemantic proximity Read ↗

Characteristics of germline DNA damage response gene mutations in ovarian cancer in Southwest China.Semantic proximity Read ↗

Multigene germline and somatic testing for epithelial ovarian cancer in ChinaSemantic proximity Read ↗

Developing a whole exome sequencing-based homologous recombination deficiency test of epithelial ovarian cancerSemantic proximity Read ↗

Homologous recombination inquiry through ovarian malignancy investigations: JGOG3025 StudySemantic proximity Read ↗

Improved detection of homologous recombination deficiency in Chinese patients with ovarian cancer: a novel non-exonic single-nucleotide polymorphism-based next-generation sequencing panel.Semantic proximity Read ↗

Large-scale integrated analysis of ovarian cancer tumors and cell lines identifies an individualized gene expression signature for predicting response to platinum-based chemotherapySemantic proximity Read ↗

Transcriptional landscape of DNA repair genes underpins a pan-cancer prognostic signature associated with cell cycle dysregulation and tumor hypoxiaSemantic proximity Read ↗

Homologous Recombination Inquiry Through Ovarian Malignancy Investigations: The Japanese Gynecologic Oncology Group study JGOG3025Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.