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Characteristics of germline DNA damage response gene mutations in ovarian cancer in Southwest China.

Scientific reports - 20 Mar 2024

Fu Kaiyu, Li Qingli, Wang Jie, Zhang Mengpei, Yan Xinyu, Li Kemin, Song Liang, Zhong Lan, Ma Yu, Chen Jinghong, Zeng Jing, Wang Danqing, Shao Di, Zhu Shida, Yin Rutie

Abstract excerpt

DNA damage response (DDR) pathways are responsible for repairing endogenous or exogenous DNA damage to maintain the stability of the cellular genome, including homologous recombination repair (HRR) pathway, mismatch repair (MMR) pathway, etc. In ovarian cancer, current studies are focused on HRR genes, especially BRCA1/2, and the results show regional and population differences. To characterize germline mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38509102
DOI: 10.1038/s41598-024-52707-y
PMCID: PMC10954728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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