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Article

Epigenetic biomarkers of colorectal cancer: Focus on DNA methylation.

Cancer letters - 28 Jan 2014

Coppedè Fabio

Abstract excerpt

The original theory of the multi-step process of colorectal cancer (CRC), suggesting that the disease resulted from the accumulation of mutations in oncogenes and tumor suppressor genes in colonic mucosa cells, has been largely revised following the observation that epigenetic modifications of several genes occur in the average CRC genome. Therefore, the current opinion is that CRCs are the consequence of the...

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PMID: 22202641
DOI: 10.1016/j.canlet.2011.12.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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