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Association of transketolase polymorphisms with diabetic polyneuropathy in the general population: The KORA F4 study.

Diabetes/metabolism research and reviews - 1 Jul 2024

Ziegler Dan, Thorand Barbara, Strom Alexander, Bönhof Gidon J, Knebel Birgit, Schleicher Erwin, Rathmann Wolfgang, Herder Christian, Maalmi Haifa, Gieger Christian, Heier Margit, Meisinger Christine, Roden Michael, Peters Annette, Grallert Harald

Abstract excerpt

AIMS: We recently reported that genetic variability in the TKT gene encoding transketolase, a key enzyme in the pentose phosphate pathway, is associated with measures of diabetic sensorimotor polyneuropathy (DSPN) in recent-onset diabetes. Here, we aimed to substantiate these findings in a population-based KORA F4 study. MATERIALS AND METHODS: In this cross-sectional study, we assessed seven single nucleotide...

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PMID: 38961642
DOI: 10.1002/dmrr.3834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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