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Prognostic relevance of high expression of kynurenine pathway markers in glioblastoma

28 Jun 2024

Abstract excerpt

Glioblastoma (GBM) continues to exhibit a discouraging survival rate despite extensive research into new treatments. One factor contributing to its poor prognosis is the tumor's immunosuppressive microenvironment, in which the kynurenine pathway (KP) plays a significant role. This study aimed to explore how KP impacts the survival of newly diagnosed GBM patients. We examined tissue samples from 108 GBM patients...

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PMID: 38951170
DOI: 10.1038/s41598-024-65907-3

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