Article
Mutagenicity of polycyclic aromatic hydrocarbons and quinones on Salmonella typhimurium TA97.
Mutation research - 1 Jan 2000
Sakai M, Yoshida D, Mizusaki S
Abstract excerpt
18 polycyclic aromatic hydrocarbons (PAHs) and 7 quinones were tested for mutagenicity using Salmonella typhimurium TA97, TA98 and TA100 with or without metabolic activation. In the presence of metabolic activation, TA97 was more susceptible to mutation than either TA98 or TA100 by many of PAHs t...
Topics
- Animals
- Biotransformation
- Microsomes, Liver
- Mutagenicity Tests
- Mutation
- Polycyclic Compounds
- Quinones
- Rats
- Salmonella typhimurium
- Species Specificity
- Structure-Activity Relationship
