Article
Mutagenicity of cyclopenta-fused polynuclear aromatic hydrocarbons and a non-polar fraction from a fuel combustion sample in a Salmonella forward mutation assay without exogenous metabolic activation.
Mutation research - 14 Jul 1997
Busby W F, Smith H, Plummer E F, Lafleur A L, Mulder P P, Boere B B, Cornelisse J, Lugtenburg J
Abstract excerpt
A series of cyclopenta-fused polynuclear aromatic hydrocarbons (PAH) were tested for mutagenicity in a bacterial forward mutation assay based on resistance to 8-azaguanine (8-AG) in Salmonella typhimurium TM677 in the absence of Aroclor-induced rat liver postmitochondrial supernatant (PMS). All o...
Topics
- Animals
- Anthracenes
- Dose-Response Relationship, Drug
- Ethylenes
- Fuel Oils
- Methylation
- Mitochondria, Liver
- Mutagenicity Tests
- Mutagens
- Mutation
- Polycyclic Aromatic Hydrocarbons