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Circulating C1q levels in health and disease, more than just a biomarker

2 Nov 2021

Abstract excerpt

C1q is the recognition molecule of the classical pathway of the complement system. By binding to its targets, such as antigen-bound immunoglobulins or C-reactive protein, C1q contributes to the innate defense against infections. However, C1q also plays several other roles beyond its traditional role in complement activation. Circulating levels of C1q are determined in routine diagnostics as biomarker in several...

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PMID: 34735869
DOI: 10.1016/j.molimm.2021.10.010

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