Article
The Importance of the FUT2 rs602662 Polymorphism in the Risk of Cardiovascular Complications in Patients after Kidney Transplantation.
International journal of molecular sciences - 14 Jun 2024
Kotowski Maciej Józef, Ostrowski Piotr, Sieńko Jerzy, Czerny Bogusław, Tejchman Karol, Machaliński Bogusław, Górska Aleksandra, Mrozikiewicz Aleksandra E, Bogacz Anna
Abstract excerpt
The FUT2 gene encodes an enzyme called α-1,2-fucosyltransferase, which is involved in the formation of blood group antigens AB0(H) and is also involved in the processes of vitamin B12 absorption and its transport between cells. FUT2 gene polymorphisms are associated with vitamin B12 levels in the body. Vitamin B12 deficiency associated with hyperhomocysteinemia is a major risk factor for cardiovascular diseases...
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