Article
Sequence analysis of the human fucosyltransferase 1 and 2 genes in Tibetan blood donors: identification of three novel alleles.
Transfusion - 1 Jul 2014
Tian Li, Song Ning, Yao Zhi-Qiang, Li Xiao-Juan, Zhang Rong
Abstract excerpt
BACKGROUND: The α(1,2)-fucosyltransferase gene 1 (FUT1) and 2 (FUT2), respectively, regulate H antigen synthesis in red blood cells and body fluids. Genetic polymorphisms of FUT1 and FUT2 are ethnically and geographically specific. STUDY DESIGN AND METHODS: Healthy unrelated Tibetan blood donors (n = 200) from the Tibet Autonomous Region of China were recruited for this study. The entire FUT1 and FUT2 coding...
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