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CircRNA Regulation of T Cells in Cancer: Unraveling Potential Targets

9 Jun 2024

Abstract excerpt

T lymphocytes play a critical role in antitumor immunity, but their exhaustion poses a significant challenge for immune evasion by malignant cells. Circular RNAs (circRNAs), characterized by their covalently closed looped structure, have emerged as pivotal regulators within the neoplastic landscape. Recent studies have highlighted their multifaceted roles in cellular processes, including gene expression...

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PMID: 38928088
DOI: 10.3390/ijms25126383

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