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Article

Silencing of circCRIM1 Drives IGF2BP1-Mediated NSCLC Immune Evasion

10 Jan 2023

Abstract excerpt

OBJECTIVES: Circular RNAs (circRNAs) have been found to have significant impacts on non-small cell lung cancer (NSCLC) progression through various mechanisms. However, the mechanism of circRNAs modulating tumor immune evasion in NSCLC has yet to be well-revealed. MATERIALS AND METHODS: Through analyzing the expression profiles of circRNAs in NSCLC tissues, RNA FISH, pull-down assay, mass spectrometry analysis,...

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PMID: 36672208
DOI: 10.3390/cells12020273

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