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RNA polymerase III is involved in regulating Plasmodium falciparum virulence

28 Feb 2024

Abstract excerpt

While often undetected and untreated, persistent seasonal asymptomatic malaria infections remain a global public health problem. Despite the presence of parasites in the peripheral blood, no symptoms develop. Disease severity is correlated with the levels of infected red blood cells (iRBCs) adhering within blood vessels. Changes in iRBC adhesion capacity have been linked to seasonal asymptomatic malaria...

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PMID: 38921824
DOI: 10.7554/elife.95879

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