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Article

The Development and Evaluation of Novel Patient Educational Material for a Variant of Uncertain Significance (VUS) Result in Hereditary Cancer Genes.

Current oncology (Toronto, Ont.) - 16 Jun 2024

Cragun Deborah, Dean Marleah, Baker David, Kelley Meghan, Hooker Gillian, Weidner Anne, Hunt Paige, Pal Tuya

Abstract excerpt

A Variant of Uncertain Significance (VUS) is a difference in the DNA sequence with uncertain consequences for gene function. A VUS in a hereditary cancer gene should not change medical care, yet some patients undergo medical procedures based on their VUS result, highlighting the unmet educational needs among patients and healthcare providers. To address this need, we developed, evaluated, and refined novel...

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Identifiers

PMID: 38920739
DOI: 10.3390/curroncol31060256
PMCID: PMC11202617

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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