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Article

SepM mutation in Streptococcus mutans clinical isolates and related function analysis.

BMC oral health - 25 Jun 2024

Liu Shanshan, Shao Yidan, Zhang Zhenzhen, Xu Wen, Liu Yudong, Zhang Kai, Xu Li, Zheng Qingwei, Sun Yu

Abstract excerpt

BACKGROUND: Streptococcus mutans (S. mutans) is an important pathogenic bacterium that causes dental caries, while Streptococcus gordonii (S. gordonii) is a non-cariogenic bacterium that inhibits the growth of S. mutans. The SepM protein can promote the inhibitory ability of S. mutans against S. gordonii by cleaving CSP-21 and activating the ComDE two-component system. This study was designed to explore sepM...

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Identifiers

PMID: 38918777
DOI: 10.1186/s12903-024-04436-x
PMCID: PMC11197336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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