Article
SepM, a Streptococcal Protease Involved in Quorum Sensing, Displays Strict Substrate Specificity.
Journal of bacteriology - 1 Feb 2016
Biswas Saswati, Cao Luyang, Kim Albert, Biswas Indranil
Abstract excerpt
UNLABELLED: Streptococcus mutans, a causative agent of dental caries, relies on multiple quorum-sensing (QS) pathways that coordinate the expression of factors needed for colonization in the oral cavity. S. mutans uses small peptides as QS signaling molecules that typically are secreted into the outside milieu. Competence-stimulating peptide (CSP) is one such QS signaling molecule that functions through the ComDE...
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