Article
Novel Cancer Prevention Strategies in Individuals With Hereditary Cancer Syndromes: Focus on BRCA1, BRCA2, and Lynch Syndrome.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting - 1 Jun 2024
Bowen Charles M, Demarest Kaitlin, Vilar Eduardo, Shah Payal D
Abstract excerpt
Germline pathogenic variants (PVs) in the BRCA1 and BRCA2 genes confer elevated risks of breast, ovarian, and other cancers. Lynch syndrome (LS) is associated with increased risks of multiple cancer types including colorectal and uterine cancers. Current cancer risk mitigation strategies have focused on pharmacologic risk reduction, enhanced surveillance, and preventive surgeries. While these approaches can be...
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