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Article

Translating Germline Cancer Risk into Precision Prevention.

Cell - 9 Feb 2017

Yurgelun Matthew B, Chenevix-Trench Georgia, Lippman Scott M

Abstract excerpt

Study of the biology of tumors caused by germline mutations has led to recent paradigm-changing therapy and is driving precision prevention efforts, including immune oncology and early detection research. Here, we explore recent biologic advances that are redefining the spectrum of cancers linked to various hereditary predisposition syndromes and can be leveraged to improve personalized risk assessment and...

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Identifiers

PMID: 28187278
DOI: 10.1016/j.cell.2017.01.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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