Article
Prevention strategies for hereditary gynaecological cancer in Lynch syndrome.
Familial cancer - 24 Mar 2026
Kwinten Kevin J J, Johnson Jean-Ellen, van Altena Anne M, Hoogerbrugge Nicoline, Davidson Emma J, de Hullu Joanne A
Abstract excerpt
Lynch syndrome is a hereditary cancer predisposition condition associated with an elevated lifetime risk of colorectal, endometrial, ovarian, and several other malignancies. This review provides an updated overview of evidence-based prevention strategies for gynaecological cancers in patients with Lynch syndrome. Risk-reducing hysterectomy with bilateral salpingo-oophorectomy is the most effective intervention...
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