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Article

The significance of CD8+ tumor-infiltrating lymphocytes exhaustion heterogeneity and its underlying mechanism in diffuse large B-cell lymphoma.

International immunopharmacology - 20 Aug 2024

Zhu Qiqi, Yang Yiming, Zeng Yi, Chen Kexin, Zhang Qiaoyu, Wang Li, Huang Yifan, Jian Shunhai

Abstract excerpt

CD8+ tumor-infiltrating lymphocytes (TILs) exhaustion is a major barrier to effective tumor control in diffuse large B-cell lymphoma (DLBCL) and may consist of heterogeneous populations with different functional states. We profiled the CD8+TILs exhaustion heterogeneity and explored its clinical significance as well as the underlying mechanism through single-cell RNA sequencing (n = 7), bulk RNA sequencing...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphocytes, Tumor-Infiltrating

Share to Lymphoma, Large B-Cell, Diffuse

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Source

Identifiers

PMID: 38909497
DOI: 10.1016/j.intimp.2024.112447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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