Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MEK Inhibition in a Pilocytic Astrocytoma With a Rare KRAS Q61R Mutation in a Young Adult Patient: A Case Report.

JCO precision oncology - 1 Jun 2024

Roberto Katrina, Keith Julia, Levine Adrian, Pirouzmand Farhad, Soliman Hany, Lim-Fat Mary Jane

Abstract excerpt

This case illustrates the utility and impact of molecular testing and molecular tumor board discussion in the management of AYA patients with brain tumors.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytoma
Share to Brain Neoplasms
Share to KRAS gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Protein Kinase Inhibitors

Share to Proto-Oncogene Proteins p21(ras)

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 38905571
DOI: 10.1200/PO.24.00174
PMCID: PMC11371098

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MEK Inhibition in a Pilocytic Astrocytoma With a Rare KRAS Q61R Mutation in a Young Adult Patient: A Case Report.PMID 38905571Read ↗

Adult pilocytic astrocytoma in the molecular era: a comprehensive reviewSemantic proximity Read ↗

A pilocytic astrocytoma with novel ATG16L1::NTRK2 fusion responsive to larotrectinib: a case report with genomic and functional analysisSemantic proximity Read ↗

Pilocytic astrocytoma harboring a novel GNAI3-BRAF fusion.Semantic proximity Read ↗

Impact of BRAF/MEK inhibitor on BRAF V600E-mutated pilocytic astrocytoma.Semantic proximity Read ↗

Dabrafenib for Pilocytic Astrocytoma With BRAF V599ins.Semantic proximity Read ↗

Targeted MAPK Pathway Inhibitors in Patients With Disseminated Pilocytic Astrocytomas.Semantic proximity Read ↗

Clinical Relevance of BRAF V600E Mutation Status in Brain Tumors with a Focus on a Novel Management Algorithm.Semantic proximity Read ↗

Integrating Molecular Analyses with the 2021 WHO Classification for a More Precise Diagnosis of Adult Pilocytic AstrocytomasSemantic proximity Read ↗

The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer.Semantic proximity Read ↗

High-Grade Astrocytoma With Piloid Features: An Aggressive Clinicogenomic Entity Distinct From Pilocytic Astrocytoma.Semantic proximity Read ↗

Activity of Pemigatinib in Pilocytic Astrocytoma and FGFR1N546K Mutation.Semantic proximity Read ↗

Adult pilocytic astrocytomas: clinical features and molecular analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.